קאנבינואידים הם תרכובות כימיות ייחודיות המופקות על-ידי צמח הקנאביס. הם מופיעים על פני הצמח בעיקר בבלוטות השרף (טריכומות) ומכונים: “Phyto-Cannabinoids” (קנבינואידים ממקור צמחי).
הקאנבינואידים מפעילים קולטנים הפזורים בכל המערכות החשובות בגופם של יונקים. הם חלק ממערכת המכונה “המערכת האנדוקנבינואידית” שתפקידה הוא וויסות ובקרה של תהליכים פיזיולוגיים בגוף (“Homeostasis”).
עד כה נתגלו כ-144 קאנבינואידים בצמח הקנאביס ולכל אחד מהם השפעה ייחודית משלו. הידועים שבהם: CBG, THC, CBD, CBC ו-CBN.
בדומה לצמח הקנאביס, גם גוף האדם מייצר חומרים דמויי קאנבינואידים המכונים ” Endo-Cannabinoids ” (קנאבואידים בגוף). כך לדוגמה: אנאנדמיד (Anandamide) אשר התגלה על-ידי פרופ’ משולם, שהנו רכיב בעל תפקיד חשוב להתפתחות העובר במהלך ההיריון.
השפעות הקנאבואידים עצמם הן מגוונות ויכולות להיות הפוכות זו מזו (למשל תיאבון או שינה). השפעות אלו תלויות גם בקאנבינואידים השונים וגם בסינרגיה בינם לבין שאר החומרים הפעילים בצמח.
השפעת הקנבינואידים השונים תלויה גם בדרך הצריכה של צמח הקנאביס 1: תהליך החימום (דה-קרבוקסילציה) ופירוק הקאנבנואידים השונים.
להמשך הכתבה עבור עמוד.
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